Discovery of yeast
The penny dropped over the next few centuries when people took a closer look at the brewing process.
First of all Dutch scientist, Leouwanhoek, examined the used brewer's yeast with a microscope and saw it was made of tiny cells. The French scientist Louis Pasteur then realised these cells were in fact living plants. These men had not so much discovered yeast (or Marmite), but they'd discovered its potential nutritional benefits, an important step.
In fact, these men should have been given medals for their contribution to society!!